Synaptojanin 1 antibody (N-Term)

Catalog No. ABIN2778875

Product Details anti-Synaptojanin 1 Antibody

Target: Synaptojanin 1 (SYNJ1)

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Pig, Rabbit, Dog, Guinea Pig, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptojanin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IDSSDEDRIS EVRKVLNSGN FYFAWSASGI SLDLSLNAHR SMQEQTTDNR

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SYNJ1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SYNJ1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1295 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Synaptojanin 1 antibody (ABIN2778875)

Thole, Vermeer, Zhang, Gadella, Nielsen: "Root hair defective4 encodes a phosphatidylinositol-4-phosphate phosphatase required for proper root hair development in Arabidopsis thaliana." in: The Plant cell, Vol. 20, Issue 2, pp. 381-95, (2008) (PubMed).

Target Details for Synaptojanin 1

Target: Synaptojanin 1 (SYNJ1)

Alternative Name: SYNJ1 (SYNJ1 Products)

Synonyms: CG6562 antibody, Dmel\\CG6562 antibody, IPP antibody, Synj antibody, fb02f11 antibody, fi15a11 antibody, nrc antibody, wu:fb02f11 antibody, wu:fi15a11 antibody, SYNJ1 antibody, INPP5G antibody, A930006D20Rik antibody, AA675315 antibody, mKIAA0910 antibody, Synaptojanin antibody, synaptojanin 1 antibody, Synj antibody, synj1 antibody, SYNJ1 antibody, Synj1 antibody

Background: Synaptojanin 1 is a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking.Synaptojanin-1 is a phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) that has a role in clathrin-coated pit dynamics Perera et al. (2006) [PubMed 17158794].[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-3383 AB020717.2 1-3383 3384-3539 AF009040.1 3318-3473 3540-4183 AF009039.1 3522-4165 4184-7039 AB020717.2 4142-6997
Alias Symbols: INPP5G
Protein Interaction Partner: UBC, GRB2, CLTC, CLTA, AP2M1, AP2A1, ITSN1, SH3KBP1, SH3GL1, AMPH, SH3GLB1, SORBS2, FNBP4, SH3BP1, EPS15, PACSIN3, PACSIN1, SH3GL2, SH3GL3, BIN1, EPHB2, CDK5, PPP3CA, PACSIN2,
Protein Size: 1295

Molecular Weight: 143 kDa

Gene ID: 8867

NCBI Accession: NM_203446, NP_982271

UniProt: O43426

Pathways: Inositol Metabolic Process, Synaptic Vesicle Exocytosis