CDC5L antibody (Middle Region)

Catalog No. ABIN2778760

Product Details anti-CDC5L Antibody

Target: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Horse, Dog, Guinea Pig, Goat, Cow, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC5L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LHWYTGEGMD EMEFTEAESN MNDLVSEYQQ YQDATADEQG EFEEEEGEDE

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CDC5L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC5L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 802 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC5L

Target: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Alternative Name: CDC5L (CDC5L Products)

Synonyms: zgc:55853 antibody, CDC5L antibody, CDC5 antibody, CDC5-LIKE antibody, CEF1 antibody, PCDC5RP antibody, dJ319D22.1 antibody, 1200002I02Rik antibody, AA408004 antibody, ARABIDOPSIS THALIANA CELL DIVISION CYCLE 5 antibody, ARABIDOPSIS THALIANA MYB DOMAIN CELL DIVISION CYCLE 5 antibody, ATCDC5 antibody, ATMYBCDC5 antibody, F21M12.15 antibody, F21M12_15 antibody, cell division cycle 5 antibody, CDC5 cell division cycle 5-like (S. pombe) antibody, cell division cycle 5 like antibody, cell division cycle 5-like antibody, cell division cycle 5 like S homeolog antibody, cell division cycle 5-like (S. pombe) antibody, cell division cycle 5 antibody, cdc5l antibody, CDC5L antibody, Chro.50385 antibody, Cdc5l antibody, cdc5l.S antibody, CDC5 antibody

Background: CDC5L shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. CDC5L has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CEF1, KIAA0432, PCDC5RP, dJ319D22.1, hCDC5, CDC5, CDC5-LIKE
Protein Interaction Partner: GOLGA2, FUS, GOLGA8F, GOLGA8EP, STAU1, UBC, LIN28A, RPA3, RPA2, RPA1, ERG, WWOX, TCP1, EED, rev, TARDBP, CSNK2A2, EMID1, CDT1, MCM10, BCAS2, GRB14, CDKN2A, CDKN1A, WHSC1, SMARCD1, ORC5, ORC2, ORC1, MCM5, MCM4, MCM3, LMO2, KRT18, EIF4A3, MAGOH, PAXIP1, MDC
Protein Size: 802

Molecular Weight: 92 kDa

Gene ID: 988

NCBI Accession: NM_001253, NP_001244

UniProt: Q99459

Pathways: Activation of Innate immune Response, Chromatin Binding