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Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) antibody

U2AF1L4 Reactivity: Human, Dog, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Goat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778747
  • Target See all Splicing factor U2AF 26 kDa subunit (U2AF1L4) Antibodies
    Splicing factor U2AF 26 kDa subunit (U2AF1L4)
    Binding Specificity
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Dog, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Goat
    Host
    • 4
    • 1
    • 1
    Rabbit
    Clonality
    • 6
    Polyclonal
    Conjugate
    • 6
    Un-conjugated
    Application
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    KIGVCRHGDR CSRLHNKPTF SQTIVLLNLY RNPQNTAQTA DGSHCHVSDV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against U2AF1L4. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human U2AF1L4
    Top Product
    Discover our top product U2AF1L4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Splicing factor U2AF 26 kDa subunit (U2AF1L4)
    Alternative Name
    U2AF1L4 (U2AF1L4 Products)
    Synonyms
    U2 small nuclear RNA auxiliary factor 1-like protein 3 antibody, U2AF1-RS3 antibody, U2AF1-like 4 antibody, U2AF1-like protein 3 antibody, U2AF1L3 antibody, U2AF1L3V1 antibody, U2AF1RS3 antibody, U2af26 antibody, AA407033 antibody, AF419339 antibody, AI451269 antibody, AW553050 antibody, TMEM149 antibody, U2 small nuclear RNA auxiliary factor 1 like 4 antibody, U2 small nuclear RNA auxiliary factor 1-like 4 antibody, U2AF1L4 antibody, U2af1l4 antibody
    Background
    U2AF1L4 is a RNA-binding protein that function as a pre-mRNA splicing factor. It plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It acts by enhancing the binding of U2AF2 to weak pyrimidine tracts and also participates in the regulation of alternative pre-mRNA splicing. It activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. U2AF1L4 binds to RNA at the AG dinucleotide at the 3'-splice site.
    Protein Interaction Partner: MDM2, SUZ12, UBC, ELAVL1, GIGYF2,
    Protein Size: 220
    Molecular Weight
    24 kDa
    Gene ID
    199746
    UniProt
    Q8WU68
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