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CARS antibody (N-Term)
CARS
Reactivity: Human, Mouse, Rat, Rabbit, Dog, Horse, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CARS Antibody
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Target
See all CARS Antibodies
CARS
(Cysteinyl-tRNA Synthetase (CARS))
Binding Specificity
All epitopes for CARS antibodies
N-Term
Reactivity
All reactivities for CARS antibodies
Human, Mouse, Rat, Rabbit, Dog, Horse, Guinea Pig
Host
All hosts for CARS antibodies
Rabbit
Clonality
All clonalities for CARS antibodies
Polyclonal
Conjugate
All conjugates for CARS antibodies
This CARS antibody is un-conjugated
Application
All applications for CARS antibodies
Western Blotting (WB)
Sequence
ADSSGQQAPD YRSILSISDE AARAQALNEH LSTRSYVQGY SLSQADVDAF
Predicted Reactivity
Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%
Characteristics
This is a rabbit polyclonal antibody against CARS. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human CARS
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for CARS
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Target
CARS
(Cysteinyl-tRNA Synthetase (CARS))
Alternative Name
CARS (CARS Products )
Synonyms
sb:cb71 antibody, CARS antibody, BcDNA:LD21177 antibody, CG8431 antibody, CRS antibody, CysRS antibody, Dmel\\CG8431 antibody, BA0089 antibody, DDBDRAFT_0215191 antibody, DDBDRAFT_0231320 antibody, DDB_0215191 antibody, DDB_0231320 antibody, DDBDRAFT_0187313 antibody, DDBDRAFT_0231318 antibody, DDB_0187313 antibody, DDB_0231318 antibody, T16B12.16 antibody, K15E6.3 antibody, K15E6_3 antibody, CARS1 antibody, CYSRS antibody, MGC:11246 antibody, CA3 antibody, cysteinyl-tRNA synthetase antibody, Cysteinyl-tRNA synthetase antibody, cysteine--tRNA ligase antibody, cysteine-tRNA ligase antibody, Cysteinyl-tRNA synthetase, class Ia family protein antibody, cysteinyl-tRNA synthetase CysS antibody, cysteinyl-tRNA synthetase S homeolog antibody, CARS antibody, cars antibody, CysRS antibody, cysS antibody, APH_RS02395 antibody, mcysS antibody, SYCO ARATH antibody, AT3G56300 antibody, AT5G38830 antibody, cars.S antibody, Cars antibody
Background
CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. CARS gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Protein Interaction Partner: UBC, DNM1L, CAND1, LUC7L2, THUMPD3, JMJD6, XPO7, FAF1, SEC23A, SEC24D, HIRIP3, HIST1H4A, TTC1, TROVE2, SHMT1, PPM1G, PPAT, PAWR, KARS, IDE, HSPA4, GFPT1, GART, GARS, APEH, APP, SUMO2, PACSIN1, PACSIN3, PACSIN2, PSTPIP1, EEF1G, Protein Size: 831
Molecular Weight
95 kDa
Gene ID
833
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