SIP1 antibody (Middle Region)

Catalog No. ABIN2778712

Product Details anti-SIP1 Antibody

Target: SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HSLIRQLARR CSEVRLLVDS KDDERVPALN LLICLVSRYF DQRDLADEPS

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 265 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SIP1

Target: SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Alternative Name: SIP1 (GEMIN2 Products)

Background: Part of the core SMN complex which plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.
Alias Symbols: GEMIN2, SIP1-delta, SIP1
Protein Interaction Partner: BMI1, RN7SL1, HDAC11, MMS19, vpr, IQCB1, GEMIN6, GEMIN7, GEMIN8, GEMIN4, RNU1-1, GEMIN5, DDX20, STRAP, SRP54, SRP9, SMN1, RNU2-1, COPA, ELAVL1, SNRPN, RAD50, IKBKG, STXBP3, SRSF4, SMN2, SRSF3, DHX9, GEMIN2, STXBP2, SNRPD1, SNRPD3, SNRPD2, SRSF2, SRSF1, U2
Protein Size: 265

Molecular Weight: 30 kDa

Gene ID: 8487

NCBI Accession: NM_001009182, NP_001009182

Pathways: Ribonucleoprotein Complex Subunit Organization, Tube Formation