DAZ2 antibody (N-Term)

Catalog No. ABIN2778701

Product Details anti-DAZ2 Antibody

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rabbit, Cow, Rat, Dog, Goat, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZ2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MDETEIGSCF GRYGSVKEVK IITNRTGVSK GYGFVSFVND VDVQKIVGSQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DAZ2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DAZ2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 534 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DAZ2

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Alternative Name: DAZ2 (DAZ2 Products)

Synonyms: pDP1678 antibody, DAZ2 antibody, deleted in azoospermia 2 antibody, deleted in azoospermia protein 2 antibody, DAZ2 antibody, LOC738583 antibody

Background: DAZ2 is a member of the DAZ family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). This RNA-binding protein is important for spermatogenesis.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: pDP1678
Protein Interaction Partner: UBC, PUM2,
Protein Size: 534

Molecular Weight: 59 kDa

Gene ID: 57055

NCBI Accession: NM_001005785, NP_001005785

UniProt: Q2KHN6