EXOSC10 antibody (C-Term)

Catalog No. ABIN2778684

Product Details anti-EXOSC10 Antibody

Target: EXOSC10 (Exosome Component 10 (EXOSC10))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rabbit, Cow, Rat, Dog, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ACKAAAEQAI SVRQQVVLEN AAKKRERATS DPRTTEQKQE KKRLKISKKP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EXOSC10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region region of human EXOSC10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 885 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-EXOSC10 antibody (ABIN2778684)

van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

Target Details for EXOSC10

Target: EXOSC10 (Exosome Component 10 (EXOSC10))

Alternative Name: EXOSC10 (EXOSC10 Products)

Synonyms: Pmscl2 antibody, zgc:55695 antibody, pm-scl antibody, pm/scl-100 antibody, pmscl antibody, pmscl2 antibody, rrp6 antibody, rrp6p antibody, EXOSC10 antibody, 201.t00018 antibody, 21.m02990 antibody, DDBDRAFT_0203581 antibody, DDBDRAFT_0233752 antibody, DDB_0203581 antibody, DDB_0233752 antibody, PM-Scl antibody, PM/Scl-100 antibody, PMSCL antibody, PMSCL2 antibody, RRP6 antibody, Rrp6p antibody, p2 antibody, p3 antibody, p4 antibody, exosome component 10 antibody, 3'-5' exonuclease antibody, exosome component 10 L homeolog antibody, exosc10 antibody, EXOSC10 antibody, EHI_021400 antibody, BBOV_IV002650 antibody, CpipJ_CPIJ003896 antibody, CMU_031760 antibody, Tsp_05247 antibody, exosc10.L antibody, Exosc10 antibody

Background: EXOSC10 contains 1 HRDC domain and 1 3'-5' exonuclease domain. Antibodies against PM/SCL are found in patients with polymyositis and/or scleroderma.
Alias Symbols: PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4
Protein Interaction Partner: SUMO2, UBC, SUMO1, RPA3, RPA2, RPA1, NOMO2, EXOSC6, FERMT3, CHPF, LSM2, EXOSC5, FOXRED1, EXOSC4, XRN1, LSM8, B9D1, USP21, UPF2, NOMO1, EXOSC7, DIS3, EXOSC8, IMMT, RUVBL2, EIF3M, TOX4, SSRP1, SKIV2L, LCAT, DXO, ALDH1B1, AICDA, ESR1, EXOSC3, EXOSC9, DIS3L,
Protein Size: 885

Molecular Weight: 101 kDa

Gene ID: 5394

NCBI Accession: NM_001001998, NP_001001998

UniProt: Q01780