PRMT3 antibody (Middle Region)

Catalog No. ABIN2778653

Product Details anti-PRMT3 Antibody

Target: PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT3 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequence: LEFSSDFTLK ITRTSMCTAI AGYFDIYFEK NCHNRVVFST GPQSTKTHWK

Predicted Reactivity: Cow: 86%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PRMT3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRMT3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 531 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRMT3

Target: PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))

Alternative Name: PRMT3 (PRMT3 Products)

Synonyms: HRMT1L3 antibody, 2010005E20Rik antibody, 2410018A17Rik antibody, AL033309 antibody, Hrmt1l3 antibody, PRMT3 antibody, hrmt1l3 antibody, zgc:112498 antibody, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 3 antibody, ATPRMT3 antibody, protein arginine methyltransferase 3 antibody, protein arginine methyltransferase 3 antibody, protein arginine N-methyltransferase 3 antibody, protein arginine methyltransferase 3 S homeolog antibody, PRMT3 antibody, Prmt3 antibody, prmt3 antibody, prmt3.S antibody

Background: Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins.Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins (Tang et al., 1998 [PubMed 9642256]).[supplied by OMIM]. Sequence Note: removed 2 bases from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2630 BC064831.1 3-2632
Alias Symbols: HRMT1L3
Protein Interaction Partner: ARFIP1, SAMHD1, XPO7, FAF1, HSPH1, SEC23A, YAP1, RASSF2, HIRIP3, HIST1H4A, USP11, XRCC5, TROVE2, PPARD, PLOD2, OSBP, NARS, LIG1, IDE, GFPT1, EIF4B, CTNNA1, HNRNPA1, VCP, STAT1, HHV8GK18_gp81, UBC, VHL, TP53, FBL, PABPN1, RPS2,
Protein Size: 531

Molecular Weight: 60 kDa

Gene ID: 10196

NCBI Accession: NM_005788, NP_005779

UniProt: O60678

Pathways: Protein targeting to Nucleus