EHF antibody (N-Term)

Catalog No. ABIN2778625

Product Details anti-EHF Antibody

Target: EHF (Ets Homologous Factor (EHF))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SCIPFQEFDI SGEHLCSMSL QEFTRAAGSA GQLLYSNLQH LKWNGQCSSD

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against Ehf. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse Ehf

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 300 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-EHF antibody (ABIN2778625)

He, Pan, Hu, Albarracin, Wu, Dai: "Profile of Ets gene expression in human breast carcinoma." in: Cancer biology & therapy, Vol. 6, Issue 1, pp. 76-82, (2007) (PubMed).

Target Details for EHF

Target: EHF (Ets Homologous Factor (EHF))

Alternative Name: Ehf (EHF Products)

Synonyms: zgc:136967 antibody, ESE3 antibody, ESE3B antibody, ESEJ antibody, 9030625L19Rik antibody, AU019492 antibody, ets homologous factor antibody, ETS homologous factor antibody, ehf antibody, EHF antibody, Ehf antibody

Background: Ehf is a transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. It may act as a repressor for a specific subset of ETS/AP-1-responsive genes, and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades. It binds to DNA sequences containing the consensus nucleotide core sequence GGAA and involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter
Alias Symbols: 9030625L19Rik, AU019492
Protein Interaction Partner: Nfkbiz,
Protein Size: 300

Molecular Weight: 33 kDa

Gene ID: 13661

NCBI Accession: NM_007914, NP_031940

UniProt: Q9NZC4