TAF1C antibody (C-Term)

Catalog No. ABIN2778623

Product Details anti-TAF1C Antibody

Target: TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))

Binding Specificity: C-Term

Reactivity: Mouse, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF1C antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RRHRGETSET QTQSKRPKRR TQLSSTFSSF TSYLDSPDAS SAPRSQDLST

Predicted Reactivity: Guinea Pig: 85%, Mouse: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Taf1c. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 836 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAF1C

Target: TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))

Alternative Name: Taf1c (TAF1C Products)

Synonyms: TAF1C antibody, Tafi95 antibody, mTAFI95 antibody, MGC:39976 antibody, SL1 antibody, TAFI110 antibody, TAFI95 antibody, TATA-box binding protein associated factor, RNA polymerase I subunit C antibody, TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa antibody, TATA-box binding protein associated factor, RNA polymerase I, C antibody, TATA-box binding protein associated factor, RNA polymerase 1 subunit C antibody, TAF1C antibody, Taf1c antibody

Background: Taf1c is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Taf1c recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
Alias Symbols: Tafi95, mTAFI95
Protein Interaction Partner: Tbp, Taf1b, Taf1a,
Protein Size: 836

Molecular Weight: 92 kDa

Gene ID: 21341

NCBI Accession: NM_021441, NP_067416

UniProt: Q6PDZ2