MLXIPL antibody (N-Term)

Catalog No. ABIN2778415

Product Details anti-MLXIPL Antibody

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLXIPL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MAGALAGLAA GLQVPRVAPS PDSDSDTDSE DPSLRRSAGG LLRSQVIHSG

Predicted Reactivity: Cow: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MLXIPL. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MLXIPL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 575 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MLXIPL

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Alternative Name: MLXIPL (MLXIPL Products)

Synonyms: ChREBP antibody, MLXIPL antibody, CHREBP antibody, MIO antibody, MONDOB antibody, WBSCR14 antibody, WS-bHLH antibody, bHLHd14 antibody, Wbscr14 antibody, MLX interacting protein-like antibody, MLX interacting protein like antibody, MLXIPL antibody, Mlxipl antibody

Background: MLXIPL is a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes.
Alias Symbols: MIO, CHREBP, MONDOB, WBSCR14, WS-bHLH, bHLHd14
Protein Interaction Partner: GRB2, MLX, NIF3L1,
Protein Size: 575

Molecular Weight: 63 kDa

Gene ID: 51085

NCBI Accession: NM_032951

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process