OTP antibody (C-Term)

Catalog No. ABIN2778383

Product Details anti-OTP Antibody

Target: OTP (Orthopedia Homeobox (OTP))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PAFPGMVPAS LPGPSNVSGS PQLCSSPDSS DVWRGTSIAS LRRKALEHTV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against OTP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human OTP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 325 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-OTP antibody (ABIN2778383)

Metwalli, Abellán, Freixes, Pross, Desfilis, Medina: "Distinct Subdivisions in the Transition Between Telencephalon and Hypothalamus Produce Otp and Sim1 Cells for the Extended Amygdala in Sauropsids." in: Frontiers in neuroanatomy, Vol. 16, pp. 883537, (2022) (PubMed).

Target Details for OTP

Target: OTP (Orthopedia Homeobox (OTP))

Alternative Name: OTP (OTP Products)

Synonyms: OTP antibody, otp antibody, BcDNA:RE58095 antibody, CG10036 antibody, CG2965 antibody, Dmel\\CG10036 antibody, Otp antibody, W26 antibody, bk24 antibody, w26 antibody, cb977 antibody, otp1 antibody, orthopedia homeobox antibody, orthopedia antibody, orthopedia homeobox a antibody, orthopedia homeobox b antibody, OTP antibody, Otp antibody, otp antibody, otpa antibody, otpb antibody

Background: OTP is a member of the homeodomain (HD) family. HD family proteins are helix-turn-helix transcription factors that play key roles in the specification of cell fates. This protein may function during brain development.This gene encodes a member of the homeodomain (HD) family. HD family proteins are helix-turn-helix transcription factors that play key roles in the specification of cell fates. This protein may function during brain development.
Protein Size: 325

Molecular Weight: 34 kDa

Gene ID: 23440

NCBI Accession: NM_032109, NP_115485

UniProt: Q5XKR4