SOX7 antibody (Middle Region)

Catalog No. ABIN2778378

Product Details anti-SOX7 Antibody

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LLGDMDRNEF DQYLNTPGHP DSATGAMALS GHVPVSQVTP TGPTETSLIS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SOX7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 388 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOX7

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Alternative Name: SOX7 (SOX7 Products)

Synonyms: sox7-A antibody, xSox7 antibody, SRY-box 7 antibody, SRY (sex determining region Y)-box 7 antibody, SRY box 7 antibody, SRY-box 7 L homeolog antibody, SOX7 antibody, Sox7 antibody, sox7 antibody, sox7.L antibody

Background: SOX7 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX7 may act as a transcriptional regulator after forming a protein complex with other proteins. It may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway.
Alias Symbols: MGC10895
Protein Interaction Partner: GLRX3, Dlg4, SMAD7, SMAD5, APP,
Protein Size: 388

Molecular Weight: 42 kDa

Gene ID: 83595

NCBI Accession: NM_031439, NP_113627

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity