TRIM8 antibody (N-Term)

Catalog No. ABIN2778368

Product Details anti-TRIM8 Antibody

Target: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RGCIGEAWAK DSGLVRCPEC NQAYNQKPGL EKNLKLTNIV EKFNALHVEK

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TRIM8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 551 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM8

Target: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Alternative Name: TRIM8 (TRIM8 Products)

Synonyms: GERP antibody, RNF27 antibody, AA408830 antibody, BB006755 antibody, Rnf27 antibody, si:ch211-208d15.5 antibody, wu:fc90g07 antibody, tripartite motif containing 8 antibody, tripartite motif containing 8 L homeolog antibody, tripartite motif-containing 8 antibody, tripartite motif containing 8b antibody, TRIM8 antibody, trim8.L antibody, Trim8 antibody, trim8b antibody

Background: TRIM8 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.
Alias Symbols: GERP, RNF27
Protein Interaction Partner: BRAP, TRIM25, PCGF5, MSL2, RNF141, TRIM2, USP7, TP53, CCNH, OTUB2, USP21, USP39, USP2, TNFAIP3, UBE2D2, TRIM47, TRIM15, TRIM8, RAD18, TRIM39, RNF111, RC3H2, RNF138, RNF181, RCHY1, RNF41, TRIM43, UHRF2, TRIM9, RNF7, TRIM24, RNF113A, MKRN3, TRAF5, TRIM21, S
Protein Size: 551

Molecular Weight: 61 kDa

Gene ID: 81603

NCBI Accession: NM_030912, NP_112174

UniProt: Q9BZR9