CSRP3 antibody (Middle Region)

Catalog No. ABIN2778310

Product Details anti-CSRP3 Antibody

Target: CSRP3 (Cysteine and Glycine-Rich Protein 3 (CSRP3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSRP3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QGAGCLSTDT GEHLGLQFQQ SPKPARSVTT SNPSKFTAKF GESEKCPRCG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CSRP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CSRP3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 194 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CSRP3 antibody (ABIN2778310)

Roberts, Childs, Brown, Davis, Booth: "Early depression of Ankrd2 and Csrp3 mRNAs in the polyribosomal and whole tissue fractions in skeletal muscle with decreased voluntary running." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 112, Issue 8, pp. 1291-9, (2012) (PubMed).

Target Details for CSRP3

Target: CSRP3 (Cysteine and Glycine-Rich Protein 3 (CSRP3))

Alternative Name: CSRP3 (CSRP3 Products)

Synonyms: CLP antibody, CMD1M antibody, CMH12 antibody, CRP3 antibody, LMO4 antibody, MLP antibody, MMLP antibody, csrp3 antibody, zgc:103468 antibody, CSRP3 antibody, csrp3-a antibody, cysteine and glycine rich protein 3 antibody, cysteine and glycine-rich protein 3 antibody, cysteine and glycine-rich protein 3 (cardiac LIM protein) antibody, cysteine and glycine rich protein 3 L homeolog antibody, CSRP3 antibody, Csrp3 antibody, csrp3 antibody, csrp3.L antibody

Background: The CSRP3 gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in CSRP3 are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans.
Alias Symbols: CLP, MLP, CRP3, LMO4, CMD1M, CMH12
Protein Interaction Partner: UBC, HDAC4, LDHD, SPTB, NHLH1, MYF6, MYOG, MYOD1, ACTN1,
Protein Size: 194

Molecular Weight: 21 kDa

Gene ID: 8048

NCBI Accession: NM_003476, NP_003467

UniProt: P50461