PREB antibody (N-Term)

Catalog No. ABIN2778276

Product Details anti-PREB Antibody

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RVENLQAVQT DFSSDPLQKV VCFNHDNTLL ATGGTDGYVR VWKVPSLEKV

Predicted Reactivity: Cow: 83%, Dog: 92%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PREB. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PREB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 417 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PREB antibody (ABIN2778276)

Edgar: "The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12." in: BMC genomics, Vol. 4, Issue 1, pp. 18, (2003) (PubMed).

Target Details for PREB

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Alternative Name: PREB (PREB Products)

Synonyms: C85705 antibody, SEC12 antibody, prolactin regulatory element binding antibody, PREB antibody, Preb antibody

Background: PREB encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p.
Alias Symbols: SEC12
Protein Interaction Partner: UBC, WWOX, vpu, HSP90AA1, CORO1C, Preb, SMAD1, TGFBR1,
Protein Size: 417

Molecular Weight: 45 kDa

Gene ID: 10113

NCBI Accession: NM_013388, NP_037520

UniProt: Q9HCU5

Pathways: ER-Nucleus Signaling