KIF2B antibody (Middle Region)

Catalog No. ABIN2778254

Product Details anti-KIF2B Antibody

Target: KIF2B (Kinesin Family Member 2B (KIF2B))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF2B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DCSKGIYALV AQDVFLLLRN STYEKLDLKV YGTFFEIYGG KVYDLLNWKK

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against KIF2B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KIF2B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 673 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KIF2B antibody (ABIN2778254)

Shrestha, Draviam: "Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK." in: Current biology : CB, Vol. 23, Issue 16, pp. 1514-26, (2013) (PubMed).

Target Details for KIF2B

Target: KIF2B (Kinesin Family Member 2B (KIF2B))

Alternative Name: KIF2B (KIF2B Products)

Synonyms: 1700063D03Rik antibody, QtsA-13688 antibody, QtsA-18420 antibody, kinensin antibody, kinesin family member 2B antibody, Kif2b antibody, KIF2B antibody

Background: KIF2B is the plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. KIF2B has microtubule depolymerization activity.
Alias Symbols: -
Protein Interaction Partner: STAU1,
Protein Size: 673

Molecular Weight: 76 kDa

Gene ID: 84643

NCBI Accession: NM_032559, NP_115948

UniProt: Q8N4N8

Pathways: Microtubule Dynamics