RGS20 antibody (Middle Region)

Catalog No. ABIN2778242

Product Details anti-RGS20 Antibody

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Zebrafish (Danio rerio), Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS20 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: NAFREFLRTE FSEENMLFWM ACEELKKEAN KNIIEEKARI IYEDYISILS

Specificity: 100 % homologous to all isoforms (1-6).

Predicted Reactivity: Cow: 86%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against RGS20. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RGS20

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 220 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS20

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Alternative Name: RGS20 (RGS20 Products)

Synonyms: RGSZ1 antibody, ZGAP1 antibody, zgc:92650 antibody, rgsz1 antibody, zgap1 antibody, GzGAP antibody, RSG20 antibody, 2900073E09Rik antibody, Rgsz1 antibody, regulator of G protein signaling 20 antibody, regulator of G-protein signaling 20 L homeolog antibody, regulator of G-protein signaling 20 antibody, RGS20 antibody, rgs20 antibody, rgs20.L antibody, Rgs20 antibody

Background: Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.
Alias Symbols: RGSZ1, ZGAP1
Protein Interaction Partner: KRTAP5-6, LCE3E, LCE2D, LCE2A, LCE1B, KLHL38, LCE4A, TBC1D16, CATSPER1, PTPMT1, KRTAP4-2, CRCT1, PVRL3, MAPKBP1, GLRX3, CREB5, PTGER3, OTX1, KRTAP5-9, INS, HSPD1, HOXA1, GNAI2, AQP1, FASLG, KIF1A, ADRB2, OSTM1, STMN2, GNAI3, GNAI1, GNAZ, UBC, GNAO1, TXLNA
Protein Size: 220

Molecular Weight: 25 kDa

Gene ID: 8601

NCBI Accession: NM_003702, NP_003693

UniProt: O76081

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling