RGS20 antibody (N-Term)

Catalog No. ABIN2778241

Product Details anti-RGS20 Antibody

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS20 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NACCFCWCCC CSCSCLTVRN QEDQRPTIAS HELRADLPTW EESPAPTLEE

Specificity: 100 % homologous to isoforms 1, 2, 4-6.

Predicted Reactivity: Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 85%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against RGS20. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 241 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS20

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Alternative Name: RGS20 (RGS20 Products)

Background: The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: RGSZ1, ZGAP1
Protein Interaction Partner: KRTAP5-6, LCE3E, LCE2D, LCE2A, LCE1B, KLHL38, LCE4A, TBC1D16, CATSPER1, PTPMT1, KRTAP4-2, CRCT1, PVRL3, MAPKBP1, GLRX3, CREB5, PTGER3, OTX1, KRTAP5-9, INS, HSPD1, HOXA1, GNAI2, AQP1, FASLG, KIF1A, ADRB2, OSTM1, STMN2, GNAI3, GNAI1, GNAZ, UBC, GNAO1, TXLNA
Protein Size: 241

Molecular Weight: 27 kDa

Gene ID: 8601

NCBI Accession: NM_003702, NP_003693

UniProt: O76081

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling