RGS13 antibody (Middle Region)

Catalog No. ABIN2778240

Product Details anti-RGS13 Antibody

Target: RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: WSRISRAKKL YKIYIQPQSP REINIDSSTR ETIIRNIQEP TETCFEEAQK

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RGS13. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RGS13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 159 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS13

Target: RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

Alternative Name: RGS13 (RGS13 Products)

Synonyms: RGD1562103 antibody, regulator of G protein signaling 13 antibody, regulator of G-protein signaling 13 antibody, RGS13 antibody, Rgs13 antibody

Background: RGS13 encodes a protein which is a member of the regulator of G protein signaling (RGS) family. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation.
Protein Interaction Partner: GNAI2, GNA11, UBC, PRKACA, CREB1, GNAQ,
Protein Size: 159

Molecular Weight: 19 kDa

Gene ID: 6003

NCBI Accession: NM_002927, NP_002918

UniProt: O14921

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling