Kv2.1/KCNB1 antibody (Middle Region)
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- Target See all Kv2.1/KCNB1 (KCNB1) Antibodies
- Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Horse, Cow, Dog, Pig, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Kv2.1/KCNB1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YIDADTDDEG QLLYSVDSSP PKSLPGSTSP KFSTGTRSEK NHFESSPLPT
- Predicted Reactivity
- Cow: 92%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against KCNB1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human KCNB1
- Top Product
- Discover our top product KCNB1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 858 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))
- Alternative Name
- KCNB1 (KCNB1 Products)
- Synonyms
- KCNB1 antibody, Kcnb1 antibody, Kcr1-1 antibody, Kv2.1 antibody, Shab antibody, DRK1PC antibody, DRK1 antibody, KV2.1 antibody, h-DRK1 antibody, potassium voltage-gated channel subfamily B member 1 antibody, potassium voltage-gated channel, Shab-related subfamily, member 1 antibody, potassium channel, voltage gated Shab related subfamily B, member 1 antibody, potassium voltage gated channel, Shab-related subfamily, member 1 antibody, KCNB1 antibody, kcnb1 antibody, LOC100541632 antibody, Kcnb1 antibody
- Background
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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DRK1, KV2.1, h-DRK1
Protein Interaction Partner: STX1A, KCNG3, KCNG4, KCNV1, KCNB2, KCNG1, KCNB1, SRC, SUMO1, NEDD4L, KCNV2, KCNG2, KCNS3, PTPRE, SNAP25, KCNH1,
Protein Size: 858 - Molecular Weight
- 96 kDa
- Gene ID
- 3745
- NCBI Accession
- NM_004975, NP_004966
- UniProt
- Q14721
- Pathways
- Synaptic Membrane
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