KIF21A antibody (N-Term)

Catalog No. ABIN2778198

Product Details anti-KIF21A Antibody

Target: KIF21A (Kinesin Family Member 21A (KIF21A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog, Horse, Cow, Rat, Guinea Pig, Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF21A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KEKRKKKSVA GKEDNTDTDQ EKKEEKGVSE RENNELEVEE SQEVSDHEDE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%, Yeast: 77%

Characteristics: This is a rabbit polyclonal antibody against KIF21A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KIF21A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1661 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KIF21A antibody (ABIN2778198)

Shen, Meza-Carmen, Puxeddu, Wang, Moss, Vaughan: "Interaction of brefeldin A-inhibited guanine nucleotide-exchange protein (BIG) 1 and kinesin motor protein KIF21A." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 48, pp. 18788-93, (2008) (PubMed).

Target Details for KIF21A

Target: KIF21A (Kinesin Family Member 21A (KIF21A))

Alternative Name: KIF21A (KIF21A Products)

Background: KIF21A belongs to a family of plus end-directed kinesin motor proteins. Neurons use kinesin and dynein microtubule-dependent motor proteins to transport essential cellular components along axonal and dendritic microtubules.
Alias Symbols: FEOM1, CFEOM1, FEOM3A
Protein Interaction Partner: NCS1, SRP72, SRP68, UBC, ELAVL1,
Protein Size: 1661

Molecular Weight: 186 kDa

Gene ID: 55605

NCBI Accession: NM_017641, NP_060111

UniProt: Q7Z4S6

Pathways: M Phase