KIF3B antibody (C-Term)

Catalog No. ABIN2778187

Product Details anti-KIF3B Antibody

Target: KIF3B (Kinesin Family Member 3B (KIF3B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF3B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: APKVQAALDA ALQDEDEIQV DASSFESTAN KKSKARPKSG RKSGSSSSSS

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KIF3B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KIF3B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 747 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KIF3B antibody (ABIN2778187)

Weisschuh, Alavi, Bonin, Wissinger: "Identification of genes that are linked with optineurin expression using a combined RNAi--microarray approach." in: Experimental eye research, Vol. 85, Issue 4, pp. 450-61, (2007) (PubMed).

Target Details for KIF3B

Target: KIF3B (Kinesin Family Member 3B (KIF3B))

Alternative Name: KIF3B (KIF3B Products)

Synonyms: FLA8 antibody, HH0048 antibody, KLP-11 antibody, AI854312 antibody, AW549267 antibody, mKIAA0359 antibody, kinesin family member 3B antibody, KIF3B antibody, Kif3b antibody

Background: The protein encoded by the KIF3B gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily.
Alias Symbols: PARP, PPOL, ADPRT, ADPRT1, PARP-1, ADPRT 1, pADPRT-1, KIF3B
Protein Interaction Partner: PARP1, CASP7, CASP3, UBE2I, TP53, SUMO2, CHFR, BANP, HUWE1, MDM2, SUMO3, DNMT1, CHD1L, IVNS1ABP, DDB2, PARP9, UBC, Rnf146, APLF, UHRF1, RPA3, RPA2, RPA1, ERG, MAFF, POLG2, RPL35, RPL27A, RPL19, RAD23A, PHB, CETN2, CETN1, DDX39A, PDLIM7, RPL14, MAFK, MAFG,
Protein Size: 747

Molecular Weight: 85 kDa

Gene ID: 142

NCBI Accession: NM_004798, NP_004789

UniProt: O15066

Pathways: Hedgehog Signaling, M Phase