KIF5B antibody (N-Term)

Catalog No. ABIN2778184

Product Details anti-KIF5B Antibody

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: CNIKVMCRFR PLNESEVNRG DKYIAKFQGE DTVVIASKPY AFDRVFQSST

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against KIF5B. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KIF5B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 963 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KIF5B antibody (ABIN2778184)

Turner, Cheng, Beckham, Keane, Norris, Liu: "Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide." in: Prostate cancer and prostatic diseases, Vol. 14, Issue 1, pp. 30-7, (2011) (PubMed).

Target Details for KIF5B

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Alternative Name: KIF5B (KIF5B Products)

Background: Kinesin is the founding member of a superfamily of microtubule based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation. Kinesin consists of heavy and light chains both of which have been documented to bind a variety of potential linker or cargo proteins. KIF5B is an isoform of kinesin heavy chain.
Alias Symbols: KNS, KINH, KNS1, UKHC
Protein Interaction Partner: ZBTB8A, HUWE1, TAX1BP1, VPS52, PRKAR2B, AURKB, STAU1, UBC, TRIM25, EZH2, PSME1, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMA5, PSMA4, KLC2, SMEK2, RNF20, ELP2, PTPN23, RABGAP1, COPE, AKAP2, COPS5, NUP50, PSMA2, KLC1, EPB41L1, DIAPH1, CAST, ACACA, YWHAE, CFTR,
Protein Size: 963

Molecular Weight: 110 kDa

Gene ID: 3799

NCBI Accession: NM_004521, NP_004512

UniProt: P33176

Pathways: Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization