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Cholesterol Esterase antibody (C-Term)

CEL Reactivity: Human, Mouse, Rat, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778160
  • Target See all Cholesterol Esterase (CEL) Antibodies
    Cholesterol Esterase (CEL)
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 36
    • 12
    • 6
    • 4
    • 3
    • 2
    Human, Mouse, Rat, Horse, Pig
    Host
    • 41
    • 4
    Rabbit
    Clonality
    • 41
    • 4
    Polyclonal
    Conjugate
    • 18
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cholesterol Esterase antibody is un-conjugated
    Application
    • 30
    • 29
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    VTPTGDSETA PVPPTGDSGA PPVPPTGDSE AAPVPPTDDS KEAQMPAVIR
    Predicted Reactivity
    Horse: 77%, Human: 100%, Mouse: 77%, Pig: 85%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against CEL. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C - terminal region of human CEL
    Top Product
    Discover our top product CEL Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 756 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Panicot-Dubois, Thomas, Furie, Furie, Lombardo, Dubois: "Bile salt-dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans." in: The Journal of clinical investigation, Vol. 117, Issue 12, pp. 3708-19, (2007) (PubMed).

  • Target
    Cholesterol Esterase (CEL)
    Alternative Name
    CEL (CEL Products)
    Synonyms
    SC8F4.24 antibody, BAL antibody, BSDL antibody, BSSL antibody, CELL antibody, CEase antibody, FAP antibody, FAPP antibody, LIPA antibody, MODY8 antibody, 1810036E18Rik antibody, Bal antibody, Bssl antibody, carboxyl ester lipase antibody, cholesterol esterase antibody, hypothetical protein antibody, CEL antibody, SCO5420 antibody, Tfu_2331 antibody, SARE_RS01070 antibody, RSal33209_1252 antibody, Caci_5976 antibody, Ndas_0054 antibody, Micau_5972 antibody, ML5_2523 antibody, Cel antibody, cel antibody
    Background
    CEL catalyzes fat and vitamin absorption. CEL acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: BAL, BSDL, BSSL, CELL, CEase, FAP, FAPP, LIPA, MODY8
    Protein Interaction Partner: OLR1, BPGM, LTF,
    Protein Size: 756
    Molecular Weight
    80 kDa
    Gene ID
    1056
    NCBI Accession
    NM_001807, NP_001798
    UniProt
    P19835
    Pathways
    Lipid Metabolism
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