ACADL antibody (Middle Region)

Catalog No. ABIN2778159

Product Details anti-ACADL Antibody

Target: ACADL (Acyl-CoA Dehydrogenase, Long Chain (ACADL))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Pig, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACADL antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LPQERLLIAD VAISASEFMF EETRNYVKQR KAFGKTVAHL QTVQHKLAEL

Predicted Reactivity: Cow: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against ACADL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACADL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 430 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ACADL antibody (ABIN2778159)

Mells, Fu, Sharma, Olson, Cheng, Handy, Saxena, Sorescu, Anania: "Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 2, pp. G225-35, (2012) (PubMed).

Target Details for ACADL

Target: ACADL (Acyl-CoA Dehydrogenase, Long Chain (ACADL))

Alternative Name: ACADL (ACADL Products)

Synonyms: zgc:55656 antibody, ACAD4 antibody, LCAD antibody, ACOADA antibody, AA960361 antibody, AU018452 antibody, C79855 antibody, acyl-CoA dehydrogenase long chain antibody, acyl-CoA dehydrogenase, long chain antibody, acyl-CoA dehydrogenase, long chain L homeolog antibody, acyl-Coenzyme A dehydrogenase, long-chain antibody, acadl antibody, ACADL antibody, Acadl antibody, acadl.L antibody

Background: ACADL belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
Alias Symbols: ACAD4, LCAD
Protein Interaction Partner: Htt, UBC,
Protein Size: 430

Molecular Weight: 44 kDa

Gene ID: 33

NCBI Accession: NM_001608, NP_001599

UniProt: P28330

Pathways: Monocarboxylic Acid Catabolic Process