Cholecystokinin antibody (Middle Region)

Catalog No. ABIN2778154

Product Details anti-Cholecystokinin Antibody

Target: Cholecystokinin (CCK)

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Cow, Pig, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cholecystokinin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IQQARKAPSG RMSIVKNLQN LDPSHRISDR DYMGWMDFGR RSAEEYEYPS

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CCK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 115 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Cholecystokinin antibody (ABIN2778154)

Talchai, Xuan, Kitamura, DePinho, Accili: "Generation of functional insulin-producing cells in the gut by Foxo1 ablation." in: Nature genetics, Vol. 44, Issue 4, pp. 406-12, S1, (2012) (PubMed).

Roskos, Wallace, Weiss: "Readability of consumer medication information for intranasal corticosteroid inhalers." in: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, Vol. 65, Issue 1, pp. 65-8, (2007) (PubMed).

Target Details for Cholecystokinin

Target: Cholecystokinin (CCK)

Alternative Name: CCK (CCK Products)

Synonyms: CCK antibody, CCK-CH antibody, cck-a antibody, cck-b antibody, cholecystokinin antibody, cholecystokinin L homeolog antibody, CCK antibody, Cck antibody, cck antibody, cck.L antibody

Background: Cholecystokinin (CCK) is a brain/gut peptide. In the gut, it induces the release of pancreatic enzymes and the contraction of the gallbladder. In the brain, its physiologic role is unclear. The cholecystokinin pro-hormone is processed by endo- and exo-proteolytic cleavages.Cholecystokinin is a brain/gut peptide. In the gut, it induces the release of pancreatic enzymes and the contraction of the gallbladder. In the brain, its physiologic role is unclear. The cholecystokinin pro-hormone is processed by endo- and exo-proteolytic cleavages. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC117187
Protein Interaction Partner: UBC, CCKBR, CCKAR, CPE, ENPEP, MEP1B, MEP1A,
Protein Size: 115

Molecular Weight: 13 kDa

Gene ID: 885

NCBI Accession: NM_000729, NP_000720

UniProt: P06307

Pathways: TCR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Feeding Behaviour