C4BPB antibody (N-Term)

Catalog No. ABIN2778139

Product Details anti-C4BPB Antibody

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Binding Specificity: N-Term

Reactivity: Human, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C4BPB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: CCLMVAWRVS ASDAEHCPEL PPVDNSIFVA KEVEGQILGT YVCIKGYHLV

Predicted Reactivity: Dog: 86%, Human: 100%, Pig: 93%

Characteristics: This is a rabbit polyclonal antibody against C4BPB. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C4BPB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 252 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-C4BPB antibody (ABIN2778139)

Emery, Erdman, Bowen, Newton, Winchell, Meyer, Tong, Cook, Holloway, McCaustland, Rota, Bankamp, Lowe, Ksiazek, Bellini, Anderson: "Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirus." in: Emerging infectious diseases, Vol. 10, Issue 2, pp. 311-6, (2004) (PubMed).

Target Details for C4BPB

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Alternative Name: C4BPB (C4BPB Products)

Synonyms: C4BPB antibody, C4BP antibody, C4bp-ps1 antibody, complement component 4 binding protein beta antibody, complement component 4 binding protein, beta antibody, C4BPB antibody, C4bpb antibody

Background: C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.
Alias Symbols: C4BP
Protein Interaction Partner: UBC, PROS1,
Protein Size: 252

Molecular Weight: 28 kDa

Gene ID: 725

NCBI Accession: NM_000716, NP_000707

UniProt: P20851

Pathways: Complement System