Asialoglycoprotein Receptor 1 antibody (Middle Region)

Catalog No. ABIN2778131

Product Details anti-Asialoglycoprotein Receptor 1 Antibody

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Pig, Saccharomyces cerevisiae, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Asialoglycoprotein Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RKMKSLESQL EKQQKDLSED HSSLLLHVKQ FVSDLRSLSC QMAALQGNGS

Predicted Reactivity: Cow: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rat: 92%, Yeast: 75%

Characteristics: This is a rabbit polyclonal antibody against ASGR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ASGR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 291 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Asialoglycoprotein Receptor 1 antibody (ABIN2778131)

Chang, Lai, Chien, Liang, Adak, Chuang, Chen, Lin: "Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions." in: Bioconjugate chemistry, Vol. 24, Issue 11, pp. 1895-906, (2013) (PubMed).

Target Details for Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Alternative Name: ASGR1 (ASGR1 Products)

Synonyms: ASGR1 antibody, ASGPR antibody, ASGPR1 antibody, CLEC4H1 antibody, HL-1 antibody, Asgr antibody, Asgr-1 antibody, ASGR antibody, RATRHL1 antibody, RHL1 antibody, asialoglycoprotein receptor 1 antibody, LOC721786 antibody, ASGR1 antibody, LOC489461 antibody, Asgr1 antibody, LOC101116157 antibody

Background: ASGR1 is a cell surface receptor binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface.
Alias Symbols: ASGPR, CLEC4H1, Hs.12056, HL-1, ASGPR1
Protein Interaction Partner: CERS2, HIVEP1, SYVN1, VKORC1, FBXO6, EDEM1, HSPA5, CANX, APP, CLEC4G, NLK, RBBP6, HSP90B1, TG, HSP90AA1, DHFR, ASGR2, ITGA1,
Protein Size: 291

Molecular Weight: 33 kDa

Gene ID: 432

NCBI Accession: NM_001671, NP_001662

UniProt: P07306

Pathways: Thyroid Hormone Synthesis