Afamin antibody (Middle Region)

Catalog No. ABIN2778130

Product Details anti-Afamin Antibody

Target: Afamin (AFM)

Binding Specificity: Middle Region

Reactivity: Human, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Afamin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GQCIINSNKD DRPKDLSLRE GKFTDSENVC QERDADPDTF FAKFTFEYSR

Predicted Reactivity: Guinea Pig: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against AFM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AFM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 599 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Afamin antibody (ABIN2778130)

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Penno, Klingler-Hoffmann, Brazzatti, Boussioutas, Putoczki, Ernst, Hoffmann: "2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer." in: Journal of proteomics, Vol. 77, pp. 40-58, (2012) (PubMed).

Target Details for Afamin

Target: Afamin (AFM)

Alternative Name: AFM (AFM Products)

Synonyms: AFM antibody, ALB2 antibody, ALBA antibody, ALF antibody, Alf antibody, alpha-Alb antibody, afamin antibody, AFM antibody, Afm antibody

Background: AFM is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. AFM is regulated developmentally, expressed in the liver and secreted into the bloodstream.This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.
Alias Symbols: ALF, ALB2, ALBA
Protein Size: 599

Molecular Weight: 69 kDa

Gene ID: 173

NCBI Accession: NM_001133, NP_001124

UniProt: P43652