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CIR1 antibody (Middle Region)

Reactivity: Human, Cow, Horse, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio), Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778094
  • Target See all CIR1 products
    CIR1
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Cow, Horse, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio), Saccharomyces cerevisiae
    Host
    • 14
    • 1
    Rabbit
    Clonality
    • 14
    • 1
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CIR1 antibody is un-conjugated
    Application
    • 8
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    GRNLTANDPS QEYVASEGEE DPEVEFLKSL TTKQKQKLLR KLDRLEKKKK
    Predicted Reactivity
    Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against CIR1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Human CIR1
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CIR1
    Abstract
    CIR1 Products
    Synonyms
    CIR antibody, 1700023B02Rik antibody, 2810021A19Rik antibody, Cicr antibody, Cir antibody, 1700023b02rik antibody, RGD1309199 antibody, corepressor interacting with RBPJ, 1 antibody, CIR1 antibody, Cir1 antibody
    Background
    CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC). CIR is also required for RBPSUH-mediated repression of transcription.
    Alias Symbols: CIR
    Protein Interaction Partner: CEP76, NEK6, U2AF1, SRSF2, SRSF1, RP9, HDAC2, SAP30, SNW1, TCEA1, NCOR2, RBPJ,
    Protein Size: 450
    Molecular Weight
    52 kDa
    Gene ID
    9541
    NCBI Accession
    NM_004882, NP_004873
    UniProt
    Q86X95
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