USP3 antibody (N-Term)

Catalog No. ABIN2778068

Product Details anti-USP3 Antibody

Target: USP3 (Ubiquitin Specific Peptidase 3 (USP3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GRYVNGHAKK HYEDAQVPLT NHKKSEKQDK VQHTVCMDCS SYSTYCYRCD

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against USP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human USP3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 520 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP3

Target: USP3 (Ubiquitin Specific Peptidase 3 (USP3))

Alternative Name: USP3 (USP3 Products)

Background: USP3 is a novel human ubiquitin-specific protease. The USP3 protein is a functional ubiquitin-specific protease in vitro, and is able to inhibit ubiquitin-dependent degradation of both an N-end Rule substrate and abnormal endogenous proteins in yeast. USP3 is also only the second known ubiquitin-specific protease capable of efficiently cleaving a ubiquitin-proline bond.
Alias Symbols: UBP, SIH003
Protein Interaction Partner: UBC, IFIH1, DDX58, TXNDC17, SH3BGRL3, TXLNG, ZFAND6, ATP6V1H, ELAVL1, TOR1AIP2, PRRC2B, NXN, RIMBP2, WDTC1, GNA13, EIF3I, EIF3H, EIF3G, EIF3F, EIF3D, EIF3C, EIF3B, EIF3A, PKLR, LRP1, GNAL, EIF4G1, CBR3,
Protein Size: 520

Molecular Weight: 59 kDa

Gene ID: 9960

NCBI Accession: NM_006537, NP_006528

UniProt: Q9Y6I4