Pirin antibody (C-Term)

Catalog No. ABIN2778062

Product Details anti-Pirin Antibody

Target: Pirin (PIR)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pirin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SHFVLIAGEP LREPVIQHGP FVMNTNEEIS QAILDFRNAK NGFERAKTWK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PIR. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PIR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 290 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Pirin

Target: Pirin (PIR)

Alternative Name: PIR (PIR Products)

Synonyms: ATPIRIN1 antibody, PRN1 antibody, pirin antibody, 2310042L19Rik antibody, Pirnl antibody, zgc:92778 antibody, xpir antibody, pirin antibody, pirin L homeolog antibody, PIR antibody, PRN antibody, Pir antibody, pir antibody, pir.L antibody

Background: PIR is a member of the cupin superfamily. The protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
Protein Interaction Partner: SMAD9, UBL7, SPEN, SUGT1, STAM, PSMB2, PPP2CA, CLNS1A, ARHGDIA, NFIX, NFKBIA, BCL3,
Protein Size: 290

Molecular Weight: 32 kDa

Gene ID: 8544

NCBI Accession: NM_003662, NP_003653

UniProt: O00625