Claudin 17 antibody (Middle Region)

Catalog No. ABIN2778040

Product Details anti-Claudin 17 Antibody

Target: Claudin 17 (CLDN17)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Horse, Sheep, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KQVQCTGSNE RAKAYLLGTS GVLFILTGIF VLIPVSWTAN IIIRDFYNPA

Predicted Reactivity: Cow: 85%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 85%

Characteristics: This is a rabbit polyclonal antibody against CLDN17. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CLDN17

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 224 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Claudin 17 antibody (ABIN2778040)

Michlig, Damak, Le Coutre: "Claudin-based permeability barriers in taste buds." in: The Journal of comparative neurology, Vol. 502, Issue 6, pp. 1003-11, (2007) (PubMed).

Target Details for Claudin 17

Target: Claudin 17 (CLDN17)

Alternative Name: CLDN17 (CLDN17 Products)

Synonyms: CLDN17 antibody, Claudin-17 antibody, zgc:173444 antibody, claudin 17 antibody, CLDN17 antibody, cldn17 antibody, Cldn17 antibody

Background: CLDN17, clustered with CLDN8 at human chromosome 21q22.11, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C.
Protein Interaction Partner: LNX1,
Protein Size: 224

Molecular Weight: 25 kDa

Gene ID: 26285

NCBI Accession: NM_012131, NP_036263

UniProt: P56750

Pathways: Cell-Cell Junction Organization, Hepatitis C