BTG2 antibody (N-Term)

Catalog No. ABIN2778006

Product Details anti-BTG2 Antibody

Target: BTG2 (BTG Family, Member 2 (BTG2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTG2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSHGKGTDML PEIAAAVGFL SSLLRTRGCV SEQRLKVFSG ALQEALTEHY

Predicted Reactivity: Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against BTG2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BTG2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 158 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-BTG2 antibody (ABIN2778006)

Tsui, Hsieh, Lin, Chang, Juang: "Triiodothyronine modulates cell proliferation of human prostatic carcinoma cells by downregulation of the B-cell translocation gene 2." in: The Prostate, Vol. 68, Issue 6, pp. 610-9, (2008) (PubMed).

Target Details for BTG2

Target: BTG2 (BTG Family, Member 2 (BTG2))

Alternative Name: BTG2 (BTG2 Products)

Synonyms: PC3 antibody, TIS21 antibody, XBtg2 antibody, BTG2 antibody, AA959598 antibody, APRO1 antibody, Pc3 antibody, Agl antibody, An antibody, Tis21 antibody, an-1 antibody, BTG family member 2 antibody, BTG anti-proliferation factor 2 antibody, B cell translocation gene 2, anti-proliferative antibody, btg2 antibody, BTG2 antibody, Btg2 antibody

Background: BTG2 is an anti-proliferative protein. BTG2 modulates transcription regulation mediated by ESR1.The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein is involved in the regulation of the G1/S transition of the cell cycle. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC126063, MGC126064, PC3, TIS21
Protein Interaction Partner: CNOT7, CNOT8, SRA1, FBXL3, FBXW2, FBXW11, BTRC, CUL1, UBC, SKP2, SKP1, HMGN1, PRMT1, PICK1, SMAD9, SMAD1, PRKCA, HOXC8, HOXB9, DYT10, CNOT1, CNOT6L,
Protein Size: 158

Molecular Weight: 17 kDa

Gene ID: 7832

NCBI Accession: NM_006763, NP_006754

UniProt: P78543

Pathways: MAPK Signaling