ZIC3 antibody (N-Term)

Catalog No. ABIN2777974

Product Details anti-ZIC3 Antibody

Target: ZIC3 (Zic Family Member 3 (ZIC3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZIC3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HHHHHTSQVP SYGGAASAAF NSTREFLFRQ RSSGLSEAAS GGGQHGLFAG

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ZIC3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZIC3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 467 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZIC3

Target: ZIC3 (Zic Family Member 3 (ZIC3))

Alternative Name: ZIC3 (ZIC3 Products)

Synonyms: HTX antibody, HTX1 antibody, VACTERLX antibody, ZNF203 antibody, RGD1561261 antibody, zic3-A antibody, Bn antibody, Zic family member 3 antibody, Zic family member 3 S homeolog antibody, zinc finger protein of the cerebellum 3 antibody, ZIC3 antibody, Zic3 antibody, zic3.S antibody

Background: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.
Alias Symbols: HTX, HTX1, ZNF203
Protein Interaction Partner: SUMO1, SRF, GLI3,
Protein Size: 467

Molecular Weight: 50 kDa

Gene ID: 7547

NCBI Accession: NM_003413, NP_003404

UniProt: O60481