WHSC1 antibody (N-Term)

Catalog No. ABIN2777965

Product Details anti-WHSC1 Antibody

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WHSC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KYNVGDLVWS KVSGYPWWPC MVSADPLLHS YTKLKGQKKS ARQYHVQFFG

Predicted Reactivity: Dog: 93%, Guinea Pig: 88%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 76%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against WHSC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WHSC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 802 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-WHSC1 antibody (ABIN2777965)

Li, Yin, Okamoto, Mushlin, Balgley, Lee, Yuan, Ikejiri, Glasker, Vortmeyer, Oldfield, Weil, Zhuang: "Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas." in: Neuro-oncology, Vol. 10, Issue 1, pp. 45-51, (2008) (PubMed).

Target Details for WHSC1

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Alternative Name: WHSC1 (WHSC1 Products)

Background: WHSC1 encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4.
Alias Symbols: WHS, NSD2, TRX5, MMSET, REIIBP
Protein Interaction Partner: HIST1H3A, HIST3H3, HDAC1, TRIM28, UBC, SF3A1, HNRNPR, MPHOSPH10, RAD50, SART3, NUP93, GTF3C4, NOLC1, DDX21, BAZ1B, DDX18, KHSRP, RRP1, SMARCA5, SMC1A, RBM10, XRCC5, VIM, EZR, TOP2B, TOP1, TMPO, SMARCA4, SFPQ, RPN1, RBBP4, RANGAP1, PTBP1, PRKDC, PLRG1, PKP
Protein Size: 802

Molecular Weight: 88 kDa

Gene ID: 7468

NCBI Accession: NM_014919, NP_055734

UniProt: O96031

Pathways: SARS-CoV-2 Protein Interactome