WHSC1 antibody (N-Term)

Catalog No. ABIN2777965

Product Details anti-WHSC1 Antibody

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WHSC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KYNVGDLVWS KVSGYPWWPC MVSADPLLHS YTKLKGQKKS ARQYHVQFFG

Predicted Reactivity: Dog: 93%, Guinea Pig: 88%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 76%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against WHSC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WHSC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 802 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-WHSC1 antibody (ABIN2777965)

Li, Yin, Okamoto, Mushlin, Balgley, Lee, Yuan, Ikejiri, Glasker, Vortmeyer, Oldfield, Weil, Zhuang: "Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas." in: Neuro-oncology, Vol. 10, Issue 1, pp. 45-51, (2008) (PubMed).

Target Details for WHSC1

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Alternative Name: WHSC1 (WHSC1 Products)

Synonyms: WHSC1 antibody, fc12c04 antibody, wu:fc12c04 antibody, wu:fi20c01 antibody, si:rp71-77d7.2 antibody, whs antibody, nsd2 antibody, trx5 antibody, mmset antibody, reiibp antibody, MMSET antibody, NSD2 antibody, REIIBP antibody, TRX5 antibody, WHS antibody, RGD1565590 antibody, 5830445G22Rik antibody, 9430010A17Rik antibody, AW555663 antibody, C130020C13Rik antibody, D030027O06Rik antibody, D930023B08Rik antibody, Whsc1l antibody, mKIAA1090 antibody, nuclear receptor binding SET domain protein 2 antibody, Wolf-Hirschhorn syndrome candidate 1 antibody, NSD2 antibody, nsd2 antibody, WHSC1 antibody, Nsd2 antibody

Background: WHSC1 encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4.
Alias Symbols: WHS, NSD2, TRX5, MMSET, REIIBP
Protein Interaction Partner: HIST1H3A, HIST3H3, HDAC1, TRIM28, UBC, SF3A1, HNRNPR, MPHOSPH10, RAD50, SART3, NUP93, GTF3C4, NOLC1, DDX21, BAZ1B, DDX18, KHSRP, RRP1, SMARCA5, SMC1A, RBM10, XRCC5, VIM, EZR, TOP2B, TOP1, TMPO, SMARCA4, SFPQ, RPN1, RBBP4, RANGAP1, PTBP1, PRKDC, PLRG1, PKP
Protein Size: 802

Molecular Weight: 88 kDa

Gene ID: 7468

NCBI Accession: NM_014919, NP_055734

UniProt: O96031

Pathways: SARS-CoV-2 Protein Interactome