TUB antibody (N-Term)
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- Target See all TUB Antibodies
- TUB (Tubby Homolog (TUB))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Horse, Dog, Rabbit, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TUB antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- DSLASVQLGA TRPTAPASAK RTKAAATAGG QGGAARKEKK GKHKGTSGPA
- Predicted Reactivity
- Dog: 92%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against TUB. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TUB
- Top Product
- Discover our top product TUB Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 561 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TUB (Tubby Homolog (TUB))
- Alternative Name
- TUB (TUB Products)
- Synonyms
- rd5 antibody, tubby antibody, MGC79522 antibody, TUB antibody, MGC80126 antibody, MGC84061 antibody, tub antibody, tubby bipartite transcription factor antibody, tubby bipartite transcription factor S homeolog antibody, tub antibody, TUB antibody, tub.S antibody, Tub antibody
- Background
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TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: rd5
Protein Interaction Partner: UBC, SUV420H2, GNAQ, SRC, ABL1, PLCG1, PIK3R1, LCK, JAK2, IRS1, GRB2,
Protein Size: 561 - Molecular Weight
- 62 kDa
- Gene ID
- 7275
- NCBI Accession
- NM_003320, NP_003311
- UniProt
- P50607
- Pathways
- RTK Signaling, Sensory Perception of Sound
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