TCEA1 antibody (N-Term)

Catalog No. ABIN2777920

Product Details anti-TCEA1 Antibody

Target: TCEA1 (Transcription Elongation Factor A Protein 1 (TCEA1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KSWKKLLDGP STEKDLDEKK KEPAITSQNS PEAREESTSS GNVSNRKDET

Predicted Reactivity: Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TCEA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TCEA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 301 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TCEA1 antibody (ABIN2777920)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Target Details for TCEA1

Target: TCEA1 (Transcription Elongation Factor A Protein 1 (TCEA1))

Alternative Name: TCEA1 (TCEA1 Products)

Synonyms: gtf2s antibody, sii antibody, tcea antibody, tf2s antibody, TCEA1 antibody, S-II antibody, GTF2S antibody, SII antibody, TCEA antibody, TF2S antibody, TFIIS antibody, fj48e12 antibody, wu:fj48e12 antibody, zgc:63975 antibody, transcription elongation factor A (SII), 1 antibody, transcription elongation factor A1 antibody, transcription elongation factor A (SII) 1 antibody, transcription elongation factor A (SII), 1 L homeolog antibody, tcea1 antibody, TCEA1 antibody, Tcea1 antibody, tcea1.L antibody

Background: TCEA1 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. TCEA1 has a role in suppression of transient pausing, which is the most important contribution of TCEA1 to elongation from a stall position. TCEA1 fuse to PLAG1 protein which is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors.
Alias Symbols: SII, TCEA, TF2S, GTF2S, TFIIS
Protein Interaction Partner: UBC, SORD, PGD, LDHA, CSE1L, BCCIP, CHORDC1, TBP, MCM5, MCM3, MCM2, GTF2H1, GTF2F1, GTF2E1, GTF2B, CDK8, MED26, POLR2C, NAA16, RBM25, SF3B2, UBAC1, POLR2A, APP, PAF1, UBR5, CDK9, LEO1, WDR61, CDC73, RTF1, CTR9, POLR2B, DDX5, INTS1, SF3B3, SNRNP200, SF3A1,
Protein Size: 301

Molecular Weight: 34 kDa

Gene ID: 6917

NCBI Accession: NM_006756, NP_006747

UniProt: P23193