T-Box 6 antibody (Middle Region)

Catalog No. ABIN2777917

Product Details anti-T-Box 6 Antibody

Target: T-Box 6 (TBX6)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AKGFRENGRN CKRERDARVK RKLRGPEPAA TEAYGSGDTP GGPCDSTLGG

Predicted Reactivity: Cow: 85%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 77%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against TBX6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 436 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-T-Box 6 antibody (ABIN2777917)

Blin, Nury, Stefanovic, Neri, Guillevic, Brinon, Bellamy, Rücker-Martin, Barbry, Bel, Bruneval, Cowan, Pouly, Mitalipov, Gouadon, Binder, Hagège, Desnos, Renaud, Menasché, Pucéat: "A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates." in: The Journal of clinical investigation, Vol. 120, Issue 4, pp. 1125-39, (2010) (PubMed).

Target Details for T-Box 6

Target: T-Box 6 (TBX6)

Alternative Name: TBX6 (TBX6 Products)

Background: TBX6 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx6. Knockout experiments in mice indicate that Tbx6 is important for specification of paraxial mesoderm structures.
Alias Symbols: DFNB67
Protein Interaction Partner: HSFY1, C1orf94, RBPMS, TOX4, PSMA3, MEOX2, PRMT1,
Protein Size: 436

Molecular Weight: 47 kDa

Gene ID: 6911

NCBI Accession: NM_004608, NP_004599

UniProt: O95947