TBX2 antibody (Middle Region)

Catalog No. ABIN487065

Product Details anti-TBX2 Antibody

Target: TBX2 (T-Box 2 (TBX2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AEIAQAEEQA RKRQEEREKE AAEQAERSQS SIVPEEEQAA NKGEEKKDDE

Predicted Reactivity: Cow: 92%, Dog: 85%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 77%, Pig: 92%, Rabbit: 92%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against TBX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 702 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TBX2

Target: TBX2 (T-Box 2 (TBX2))

Alternative Name: TBX2 (TBX2 Products)

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX2 is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ10169
Protein Interaction Partner: SOX2, SUMO1, EGR1, LZTR1, CEBPE, NKX2-5,
Protein Size: 702

Molecular Weight: 74 kDa

Gene ID: 6909

NCBI Accession: NM_005994, NP_005985

UniProt: Q13207

Pathways: p53 Signaling