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T-Box 1 antibody (C-Term)

TBX1 Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Dog WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777912
  • Target See all T-Box 1 (TBX1) Antibodies
    T-Box 1 (TBX1)
    Binding Specificity
    • 16
    • 12
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 58
    • 20
    • 19
    • 3
    • 3
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Rabbit, Dog
    Host
    • 56
    • 2
    • 1
    Rabbit
    Clonality
    • 57
    • 2
    Polyclonal
    Conjugate
    • 23
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This T-Box 1 antibody is un-conjugated
    Application
    • 47
    • 24
    • 19
    • 19
    • 14
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    PNPELRLEAP GASEPLHHHP YKYPAAAYDH YLGAKSRPAP YPLPGLRGHG
    Predicted Reactivity
    Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against TBX1. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human TBX1
    Top Product
    Discover our top product TBX1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 495 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    T-Box 1 (TBX1)
    Alternative Name
    TBX1 (TBX1 Products)
    Synonyms
    CAFS antibody, CTHM antibody, DGCR antibody, DGS antibody, DORV antibody, TBX1C antibody, TGA antibody, VCFS antibody, mp:zf637-3-000616 antibody, zgc:136724 antibody, TBX1 antibody, dgs antibody, tga antibody, cafs antibody, cthm antibody, dgcr antibody, dorv antibody, vcfs antibody, tbx1c antibody, xtbx1 antibody, tbx1 antibody, T-box 1 antibody, T-box 1 S homeolog antibody, T-box 1 L homeolog antibody, TBX1 antibody, Tbx1 antibody, tbx1 antibody, tbx1.S antibody, tbx1.L antibody
    Background
    TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX1 product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where TBX1 has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: DGS, TGA, CAFS, CTHM, DGCR, DORV, VCFS, TBX1C
    Protein Interaction Partner: TERF2, TERF1,
    Protein Size: 495
    Molecular Weight
    53 kDa
    Gene ID
    6899
    NCBI Accession
    NM_080647, NP_542378
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation
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