SUPT5H antibody (C-Term)

Catalog No. ABIN2777903

Product Details anti-SUPT5H Antibody

Target: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Binding Specificity: C-Term

Reactivity: Human, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUPT5H antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PYAAPSPQGS YQPSPSPQSY HQVAPSPAGY QNTHSPASYH PTPSPMAYQA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against SUPT5H. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SUPT5H

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1087 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SUPT5H

Target: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Alternative Name: SUPT5H (SUPT5H Products)

Background: SUPT5H and its binding partner regulate transcriptional elongation by RNA polymerase II. SPT4 and SPT5 are involved in both 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB)-mediated transcriptional inhibition and the activation of transcriptional elongation by the human immunodeficiency virus type 1 (HIV-1) Tat protein.
Alias Symbols: SPT5, SPT5H, Tat-CT1
Protein Interaction Partner: POLR2A, BRCA1, UBC, RNF2, SAMHD1, GANAB, SWAP70, PAICS, CARM1, FARSB, SEC24C, RANBP3, CSDE1, SF1, SET, PLOD2, MSH2, MSH6, GART, XRCC6, ATP6V1B2, SOX2, LMNA, CDK9, CCNT2, CCNT1, tat, NSMF, FN1, CSNK2A1, SIK1, ZNF512B, LMAN2, ZFYVE9, SNX4, SUPT4H1, POLR2C,
Protein Size: 1087

Molecular Weight: 121 kDa

Gene ID: 6829

NCBI Accession: NM_003169, NP_003160

UniProt: O00267