SOX12 antibody (C-Term)

Catalog No. ABIN2777869

Product Details anti-SOX12 Antibody

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Guinea Pig, Dog, Rat, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DCSALDRDPD LQPPSGTSHF EFPDYCTPEV TEMIAGDWRP SSIADLVFTY

Predicted Reactivity: Dog: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against SOX12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SOX12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 315 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SOX12 antibody (ABIN2777869)

Satoh, Tada, Tachiki, Tsuchiya, Shimoda, Akao, Sato, Habuchi, Suzuki, Kato: "Chrono and clinical pharmacokinetic study of tacrolimus in continuous intravenous administration." in: International journal of urology : official journal of the Japanese Urological Association, Vol. 8, Issue 7, pp. 353-8, (2001) (PubMed).

Target Details for SOX12

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Alternative Name: SOX12 (SOX12 Products)

Synonyms: SOX22 antibody, sox-k1 antibody, sox-k1-a antibody, sox33 antibody, xSox-33 antibody, xSox-K1 antibody, xSox33 antibody, 2010205A02Rik antibody, SRY-box 12 antibody, SRY box 12 antibody, SRY-box 12 S homeolog antibody, SRY (sex determining region Y)-box 12 antibody, SOX12 antibody, Sox12 antibody, sox12.S antibody

Background: Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.
Alias Symbols: SOX22
Protein Interaction Partner: SRM, POLD2, SMAD4,
Protein Size: 315

Molecular Weight: 34 kDa

Gene ID: 6666

NCBI Accession: NM_006943, NP_008874

UniProt: O15370