SOX3 antibody (N-Term)

Catalog No. ABIN2777860

Product Details anti-SOX3 Antibody

Target: SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LETELKNPVG TPTQAAGTGG PAAPGGAGKS SANAAGGANS GGGSSGGASG

Predicted Reactivity: Dog: 85%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 85%

Characteristics: This is a rabbit polyclonal antibody against SOX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SOX3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 446 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOX3

Target: SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

Alternative Name: SOX3 (SOX3 Products)

Synonyms: GHDX antibody, MRGH antibody, PHP antibody, PHPX antibody, SOXB antibody, CH3 antibody, Sry antibody, Xlsox3 antibody, Xtsox3 antibody, mrgh antibody, soxb antibody, xSox3 antibody, Sox-3 antibody, fc93f07 antibody, id:ibd2036 antibody, sb:cb493 antibody, wu:fc93f07 antibody, wu:fd02a08 antibody, zgc:110279 antibody, sox3-a antibody, xSox-B1 antibody, SRY-box 3 antibody, transcription factor SOX-3 antibody, SRY (sex determining region Y)-box 3 antibody, SRY-box 3 S homeolog antibody, SOX3 antibody, Tsp_06143 antibody, sox3 antibody, Sox3 antibody, sox3.S antibody

Background: SOX3 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.
Alias Symbols: PHP, GHDX, MRGH, PHPX, SOXB
Protein Interaction Partner: TRRAP, SUMO1, SUMO2, PAX6,
Protein Size: 446

Molecular Weight: 45 kDa

Gene ID: 6658

NCBI Accession: NM_005634, NP_005625

UniProt: P41225