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SIAH2 antibody (Middle Region)

SIAH2 Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777843
  • Target See all SIAH2 Antibodies
    SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 36
    • 15
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Guinea Pig, Horse, Rabbit
    Host
    • 34
    • 2
    Rabbit
    Clonality
    • 34
    • 2
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIAH2 antibody is un-conjugated
    Application
    • 23
    • 21
    • 20
    • 13
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    AVDWVMMQSC FGHHFMLVLE KQEKYEGHQQ FFAIVLLIGT RKQAENFAYR
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SIAH2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SIAH2
    Top Product
    Discover our top product SIAH2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 324 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))
    Alternative Name
    SIAH2 (SIAH2 Products)
    Synonyms
    hSiah2 antibody, Xsiah-2 antibody, siah2-A antibody, xsiah2 antibody, AA415433 antibody, Sinh2 antibody, siah E3 ubiquitin protein ligase 2 antibody, siah E3 ubiquitin protein ligase 2 L homeolog antibody, seven in absentia 2 antibody, SIAH2 antibody, siah2.L antibody, Siah2 antibody
    Background
    SIAH2 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: hSiah2
    Protein Interaction Partner: EGLN3, XAF1, HIPK2, UBE2D1, UBE2L6, SIAH2, UBE2D3, UBC, PPP1R13B, TP53BP2, NFE2L2, USP19, AR, UBE2I, STAT3, MYD88, EEF1D, CCBE1, SETD2, HIPK3, TNK2, KAT5, KAT2B, UBE2D2, TPX2, PML, ATN1, PSMD4, PPP1R12A, EGLN2, SH3RF1, EGLN1, DYRK2, PPP1CC, AFF1, DCC, CEB
    Protein Size: 324
    Molecular Weight
    34 kDa
    Gene ID
    6478
    NCBI Accession
    NM_005067, NP_005058
    UniProt
    O43255
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