Cyclin L1 antibody (N-Term)

Catalog No. ABIN2777789

Product Details anti-Cyclin L1 Antibody

Target: Cyclin L1 (CCNL1)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin L1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TTTTTTGGIL IGDRLYSEVS LTIDHSLIPE ERLSPTPSMQ DGLDLPSETD

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CCNL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCNL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 526 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cyclin L1

Target: Cyclin L1 (CCNL1)

Alternative Name: CCNL1 (CCNL1 Products)

Background: CCNL1 plays a critical role in the loco-regional progression of HNSCC and may serve as an indicator for occult advanced tumour stages. CCNL1 also plays a role in pre-mRNA splicing, has been shown to associate with the PITSLRE kinase, and is involved in pre-mRNA processing.
Alias Symbols: ANIA6A, BM-001, PRO1073, ania-6a
Protein Interaction Partner: TFIP11, APPBP2, SUMO1, UBC, NEDD8, JMJD6, CSNK2A2, APP, ISG15, SRSF2, CDK11A,
Protein Size: 526

Molecular Weight: 60 kDa

Gene ID: 57018

NCBI Accession: NM_020307, NP_064703

UniProt: Q8NI48