IVNS1ABP antibody (N-Term)

Catalog No. ABIN2777748

Product Details anti-IVNS1ABP Antibody

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig, Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IVNS1ABP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RAVLACCSPY LFEIFNSDSD PHGISHVKFD DLNPEAVEVL LNYAYTAQLK

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against IVNS1ABP. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IVNS1ABP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 642 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IVNS1ABP

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Alternative Name: IVNS1ABP (IVNS1ABP Products)

Synonyms: 1190004M08Rik antibody, 1700126I16Rik antibody, AA960440 antibody, HSPC068 antibody, ND1 antibody, NS-1 antibody, NS1-BP antibody, Nd1-L antibody, Nd1-S antibody, mKIAA0850 antibody, cb1052 antibody, fj23g11 antibody, ivns1abp antibody, wu:fj23g11 antibody, FLARA3 antibody, KLHL39 antibody, NS1BP antibody, fi13f08 antibody, fi41c09 antibody, wu:fi13f08 antibody, wu:fi41c09 antibody, influenza virus NS1A binding protein antibody, influenza virus NS1A binding protein a antibody, influenza virus NS1A binding protein L homeolog antibody, influenza virus NS1A binding protein b antibody, Ivns1abp antibody, ivns1abpa antibody, ivns1abp.L antibody, IVNS1ABP antibody, ivns1abpb antibody

Target Type: Influenza Protein

Background: This gene encodes a protein which interacts with the nonstructural NS1 protein of the influenza A virus. In noninfected cells, affinity-purified antibodies localized this protein in nuclear regions enriched with the spliceosome assembly factor SC35, suggesting an association with the cellular splicing apparatus. In influenza A virus-infected cells, the protein relocalized throughout the nucleoplasm and appeared distinct from the SC35 domains, which suggests that its function may be disturbed or altered.
Alias Symbols: ND1, NS-1, NS1BP, FLARA3, KLHL39, NS1-BP, HSPC068
Protein Interaction Partner: UBC, DHX36, PARP1, ACTB, ZC3HAV1, RBMX, LARP1, DHX30, HNRNPUL1, IGF2BP1, IVNS1ABP, DDX17, HNRNPR, LRPPRC, THRAP3, G3BP2, DDX21, PABPC4, GBF1, STAU1, UPF1, POLR2A, YBX1, NCBP1, HNRNPM, MYH9, ILF3, ILF2, HSP90AB1, HSPA8, HNRNPU, HNRNPL, HNRNPK, HNRNPF, HNRN
Protein Size: 642

Molecular Weight: 72 kDa

Gene ID: 10625

NCBI Accession: NM_006469, NP_006460

UniProt: Q9Y6Y0

Pathways: Negative Regulation of intrinsic apoptotic Signaling