SLC38A2 antibody (N-Term)

Catalog No. ABIN2777727

Product Details anti-SLC38A2 Antibody

Target: SLC38A2 (Solute Carrier Family 38, Member 2 (SLC38A2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC38A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AALKSHYADV DPENQNFLLE SNLGKKKYET EFHPGTTSFG MSVFNLSNAI

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SLC38A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC38A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 506 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC38A2 antibody (ABIN2777727)

Hernandez-García, Manjarín, Suryawan, Nguyen, Davis, Orellana: "Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia." in: Pediatric research, Vol. 80, Issue 3, pp. 448-51, (2016) (PubMed).

Suryawan, Nguyen, Almonaci, Davis: "Abundance of amino acid transporters involved in mTORC1 activation in skeletal muscle of neonatal pigs is developmentally regulated." in: Amino acids, Vol. 45, Issue 3, pp. 523-30, (2013) (PubMed).

Target Details for SLC38A2

Target: SLC38A2 (Solute Carrier Family 38, Member 2 (SLC38A2))

Alternative Name: SLC38A2 (SLC38A2 Products)

Synonyms: SLC38A2 antibody, slc38a2 antibody, snat2 antibody, ATA2 antibody, PRO1068 antibody, SAT2 antibody, SNAT2 antibody, 5033402L14Rik antibody, AI316867 antibody, mKIAA1382 antibody, Ata2 antibody, Atrc2 antibody, Sat2 antibody, Snat2 antibody, solute carrier family 38 member 2 antibody, solute carrier family 38, member 2 antibody, solute carrier family 38 member 2 L homeolog antibody, SLC38A2 antibody, slc38a2 antibody, Slc38a2 antibody, slc38a2.L antibody

Background: Under hypertonic conditions the induction of SLC38A2/SNAT2 leads to the stimulation of transport system A and to the increase in the cell content of amino acids. Its amino acid response element, along with a nearby conserved CAAT box, has enhancer activity in that it functions in an orientation and position independent manner, and it confers regulated transcription to a heterologous promoter.
Alias Symbols: ATA2, KIAA1382, PRO1068, SAT2, SNAT2
Protein Interaction Partner: UBC, APP, MCU, FLOT1, COX5A, ELAVL1, STX11,
Protein Size: 506

Molecular Weight: 56 kDa

Gene ID: 54407

NCBI Accession: NM_018976, NP_061849

UniProt: Q96QD8

Pathways: Dicarboxylic Acid Transport