PCYOX1 antibody (C-Term)

Catalog No. ABIN2777705

Product Details anti-PCYOX1 Antibody

Target: PCYOX1 (Prenylcysteine Oxidase 1 (PCYOX1))

Binding Specificity: C-Term

Reactivity: Human, Cow, Dog, Horse, Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCYOX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: IFSQETLTKA QILKLFLSYD YAVKKPWLAY PHYKPPEKCP SIILHDRLYY

Predicted Reactivity: Cow: 83%, Dog: 86%, Horse: 86%, Human: 100%, Pig: 83%, Rabbit: 100%, Yeast: 75%

Characteristics: This is a rabbit polyclonal antibody against PCYOX1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PCYOX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 505 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCYOX1

Target: PCYOX1 (Prenylcysteine Oxidase 1 (PCYOX1))

Alternative Name: PCYOX1 (PCYOX1 Products)

Synonyms: PCL1 antibody, 1200015P13Rik antibody, AI115532 antibody, AI448340 antibody, Pcly antibody, Clp55 antibody, pcl1 antibody, zgc:110246 antibody, prenylcysteine oxidase 1 antibody, PCYOX1 antibody, Pcyox1 antibody, pcyox1 antibody

Background: Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.
Alias Symbols: PCL1
Protein Interaction Partner: UBC, SLC9A3R1, NDUFV2,
Protein Size: 505

Molecular Weight: 57 kDa

Gene ID: 51449

NCBI Accession: NM_016297, NP_057381

UniProt: Q9UHG3